Serum and urine concentrations of trypsinogen-activation peptide as markers for acute pancreatitis in cats |
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Authors: | Heidi S Allen Jrg Steiner John Broussard Caroline Mansfield David A Williams and Boyd Jones |
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Institution: | The Bobst Hospital, Animal Medical Center, New York, New York 10021, USA. RUN.DVM@Verizon.net |
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Abstract: | The purpose of this study was to compare the clinical utility of the serum concentration of feline trypsin-like immunoreactivity (fTLI), the plasma and urine concentrations of trypsinogen-activation peptide (TAP), and the ratio of the urine TAP and creatinine concentrations (TAP:Cr) in the diagnosis of feline acute pancreatitis. We used 13 healthy cats and 10 cats with a diagnosis of acute pancreatitis. The mean serum fTLI and plasma TAP concentrations were significantly higher in the cats with acute pancreatitis than in the healthy cats (P < 0.05); the mean urine TAP concentrations and the median urine TAP:Cr ratios were not significantly different. Among the cats examined in this study, there was no benefit of plasma TAP over serum fTLI in the evaluation of suspected acute pancreatitis. |
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