| Affiliation: | 1. Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia;2. School of Veterinary Science, The University of Queensland, Gatton, Queensland, Australia;3. Department of Microbiology and Molecular Pathology, Sullivan Nicolaides Pathology, Brisbane, Queensland, Australia;4. Centre for Veterinary Education, University of Sydney, Sydney, New South Wales, Australia School of Animal and Veterinary Sciences, Albert Pugsley Pl, Charles Sturt University, New South Wales, Australia;5. Elizabeth MacArthur Agricultural Institute, NSW Department Primary Industries, Menangle, New South Wales, Australia;6. Institute of Infection, Veterinary and Ecological Sciences, The University of Liverpool, Liverpool, UK |
| Abstract: | Brucella suis is an emerging, zoonotic disease predominantly affecting dogs and humans that engage in feral pig hunting in Australia and other countries. Although B. suis infection in dogs shares some clinical similarities to the host-adapted species (B. canis), B. suis remains an incompletely understood pathogen in dogs with limited published data on its pathogenesis and clinical features. This case series describes the presentations, diagnosis, and clinical management of B. suis infection in three dogs: (1) a bitch with dystocia, abortion and mastitis; (2) an entire male dog with septic arthritis and presumptive osteomyelitis; and (3) a castrated male dog with lymphadenitis. Unique features of these cases are reported including the first documented detection of B. suis from milk and isolation from lymph nodes of canine patients, as well as the follow-up of pups born to a B. suis-infected bitch. Consistent with previous reports, all three dogs showed a favourable clinical response to combination antibiotic therapy with rifampicin and doxycycline. Individually tailored drug regimens were required based on the clinical presentation and other factors, including owner expectations and compliance with therapy as well as a zoonotic risk assessment (generally considered low, except around time of whelping). The authors include their recommendations for the clinical management of dogs that are at-risk or seropositive for B. suis with or without clinical signs or laboratory-confirmed infection. |
