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双波长紫外分光光度法测定酒石酸泰乐菌素-盐酸多西环素可溶性粉的含量
引用本文:仲晓宁,都波,魏妹红. 双波长紫外分光光度法测定酒石酸泰乐菌素-盐酸多西环素可溶性粉的含量[J]. 中国兽药杂志, 2006, 40(3): 20-22
作者姓名:仲晓宁  都波  魏妹红
作者单位:1. 烟台市畜牧检测中心,山东,烟台,264003
2. 山东省医药工业设计院,山东,济南,250013
3. 青岛澳海药业有限公司,山东,青岛,266101
摘    要:建立了双波长紫外分光光度法同时测定酒石酸泰乐菌素-盐酸多西环素可溶性粉中酒石酸泰乐菌素和盐酸多西环素含量的检测方法。结果显示,吸收度与浓度呈良好线性关系。酒石酸泰乐菌素的平均回收率为99.90%,RSD为0.42%n=5);盐酸多西环素的平均回收率为100.07%,RSD为0.74%(n=5)。

关 键 词:双波长紫外分光光度法  酒石酸泰乐菌素  盐酸多西环素
文章编号:1002-1280(2006)03-0020-03
收稿时间:2005-07-01
修稿时间:2005-07-01

Determination of Tylosin Tartrate and Doxycycline Hyclate Soluble Powder by Ultraviolet Spectrophotometry
ZHONG Xiao-ning,DU Bo,WEI Mei-hong. Determination of Tylosin Tartrate and Doxycycline Hyclate Soluble Powder by Ultraviolet Spectrophotometry[J]. Chinese Journal of Veterinary Drug, 2006, 40(3): 20-22
Authors:ZHONG Xiao-ning  DU Bo  WEI Mei-hong
Affiliation:1. Yantai Animal Husbandry Monitoring Center, Yantai,Shandong 264003 ; 2. Shandong Pharmaceutical Industry Designing Institute, Jinan,Shandong 250013; 3. Qingdao Aohai Pharmaceutical Co. ,Ltd. ,Qingdao,Shandong 266101 ;China
Abstract:An ultraviolet spectrophotometry was established to determine the tylosin tartrate and doxycycline hyclate content in the tylosin tartrate and doxycycline hyclate soluble powder.The relationship between the absorbance and the concentration of two drugs was linear.The mean recovery was 99.90%(RSD=0.42%) for tylosin tartrate and 100.07%(RSD=0.74%)for doxycycline hyclate.It proved that the method is suitable for the determination of tylosin tartrate and doxycycline hyclate soluble powder.
Keywords:ultraviolet spectrophotometry   tylosin tartrate    doxycycline hyclate
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