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Rapid vacuolar sequestration: the horseweed glyphosate resistance mechanism
Authors:Xia Ge  D André d'Avignon  Joseph JH Ackerman  R Douglas Sammons
Institution:1. Department of Chemistry, Washington University, St Louis, MO, USA;2. Department of Radiology, Washington University, St Louis, MO, USA;3. Department of Internal Medicine, Washington University, St Louis, MO, USA;4. Monsanto Company, St Louis, MO, USA
Abstract:BACKGROUND: Glyphosate‐resistant (GR) weed species are now found with increasing frequency and threaten the critically important GR weed management system. RESULTS: The reported 31P NMR experiments on glyphosate‐sensitive (S) and glyphosate‐resistant (R) horseweed, Conyza canadensis (L.) Cronq., show significantly more accumulation of glyphosate within the R biotype vacuole. CONCLUSIONS: Selective sequestration of glyphosate into the vacuole confers the observed horseweed resistance to glyphosate. This observation represents the first clear evidence for the glyphosate resistance mechanism in C. canadensis. Copyright © 2010 Society of Chemical Industry
Keywords:glyphosate  glyphosate‐resistant  in vivo 31P NMR  Conyza canadensis
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