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Bioavailability of oxytetracycline from medicated feed administered to Atlantic salmon (Salmo salar L.) in seawater
Institution:1. State Key Lab for Metal Matrix Composites, Key Lab of Artificial Structures & Quantum Control (Ministry of Education), School of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China;2. Collaborative Innovation Center of Advanced Microstructures, Nanjing 210093, China;3. State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, China
Abstract:Bioavailability of oxytetracycline HCl was investigated in Atlantic salmon (Salmo salar L.) in seawater at 7–8 °C. A group of 80 fish received an intravascular injection of 20 mg kg−1 body weight. Another group of about 90 fish were force-fed with medicated feed containing a dose of 50 mg kg−1 body weight. The oral bioavailability was found to be only 2%.
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