Metallothionein and metal levels in liver,gills and kidney of <Emphasis Type="Italic">Sparus aurata</Emphasis> exposed to sublethal doses of cadmium and copper |
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| Authors: | J Ghedira J Jebali Z Bouraoui M Banni H Guerbej H Boussetta |
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| Institution: | 1.Laboratoire de Biochimie et de Toxicologie Environnementale,Institut Supérieur d’Agronomie de Chott-Mariem,Sousse,Tunisia;2.Laboratoire d’Aquaculture,INSTM de Monastir,Monastir,Tunisia |
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| Abstract: | The levels of metallothionein (MT), a biomarker of metal exposure, and of Cd and Cu, known as MT inducers, were investigated
in Sparus aurata intraperitoneally injected with 500 μg/kg of Cu and Cd for 2 days. MT and metal concentrations (Cd and Cu) were determined
in liver, gills and kidney. MT levels were significantly increased in all investigated tissues, with the highest value in
liver of Cu as Cd-treated fishes (3.56-fold and 3.3- fold, respectively). Metal concentrations were statistically different
between all tissues. Highest metal concentrations were in the liver. The higher metal concentrations and MT induction levels
support the main role of MT in metal homeostasis and detoxification. |
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