Hoxc13 Expression Pattern in Cashmere Goat Skin During Hair Follicle Development |
| |
Authors: | WU Jiang-hong ZHANG Wen-guang LI Jin-quan YIN Jun ZHANG Yan-jun |
| |
Institution: | 1. Key Laboratory of Animal Genetics,Breeding and Reproduction,Nei Mongol Autonomous Region,Hohhot 010018,P.R.China;College of Animal Science and Medicine,Inner Mongolia Agricultural University,Hohhot 010018,P.R.China 2. College of Animal Science and Medicine,Inner Mongolia Agricultural University,Hohhot 010018,P.R.China 3. Key Laboratory of Animal Genetics,Breeding and Reproduction,Nei Mongol Autonomous Region,Hohhot 010018,P.R.China 4. College of Bioengineering,Inner Mongolia Agricultural University,Hohhot 010018,P.R.China |
| |
Abstract: | Hoxc13 has an important role in controlling hair formation.In this study,we examine the Hoxc13 RNA expression pattern of skin during embryo development.The result indicated that changes of the Hoxc13 gene expression and thickness of skin have a similar trend during hair follicle morphogenesis.In interpreting these results,we investigated whether the regulation motifs is in Hoxc13 intron,which is a 5.4 kb fragment.To blast with other mammals,we found a very conservative region in all mammal animals and two regions in livestock,such as cow,sheep,horse,dog,and so on,which are not in other Hox genes.We have examined putative pre-miRNA in this region,providing an entry point for elucidating currently unknown mechanisms that are required for regulating quantitative levels of Hoxc13 gene expression. |
| |
Keywords: | Hoxc13 gene expression Cashmere goat hair follicle |
本文献已被 维普 万方数据 ScienceDirect 等数据库收录! |
|