Myocardial dysfunction resulting from coronary microembolization

Coronary microembolization is a significant and frequent complication of primary percutaneous coronary intervention in the patients with acute myocardial infarction. More importantly, coronary microembolization is a main reason of dysfunction of microcirculation. The mechanism of myocardial disfunction resulting from coronary microembolition was associated with the vascular active materials released from platelet, platelet aggregation, which aggravate microembolization in microcirculation, endothelial dysfunction and inflammation.