Effects of alpha‐lipoic acid supplementation on growth performance,antioxidant capacity and biochemical parameters for ammonia‐exposed broilers |
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| Authors: | Fengxian Wei Bin Xu Quanyou Sun Jie Li Gaili Wang Xiangfang Tang Hongfu Zhang Qingqiang Yin Shaoyu Li |
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| Institution: | 1. Institute of Animal Husbandry and Veterinary Science, Henan Academy of Agricultural Sciences, Zhengzhou, China;2. State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, The Chinese Academy of Agricultural Sciences, Beijing, China;3. College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, China |
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| Abstract: | In order to estimate the effect of alpha‐lipoic acid (LA) supplementation on relieving ammonia stress of broilers, 180 22‐day‐old male broilers were assigned to three groups, six replicates in each group and 10 birds per replicate. The three groups were: (1) a control group without ammonia stress; (2) exposure to 70 ppm atmospheric ammonia (AM); (3) exposure to 70 ppm atmospheric ammonia and administration of 300 mg/kg LA (AM + LA). The experimental period was 3 weeks. Results showed that average daily weight gain was increased and feed conversion ratio was decreased in the AM + LA group, compared with the AM group (P < 0.05). Total superoxide dismutase and glutathione peroxidase activities in serum, and glutathione content in liver were higher in the AM + LA group than that in the AM group (P < 0.05); however, serum malondialdehyde content was decreased by LA addition (P < 0.05). Additionally, serum glutamic‐pyruvic transaminase, creatine kinase and lactate dehydrogenase activities were reduced and albumin level was increased by LA addition (P < 0.05). In conclusion, LA addition could relieve ammonia stress to restore broiler production performance to normal levels. |
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| Keywords: | alpha‐lipoic acid ammonia stress antioxidant capability broiler growth performance |
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