| 家蝇抗菌肽及其基因工程研究进展 |
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| 引用本文： | 王鑫,刘晖,沈玉娟,曹建平.家蝇抗菌肽及其基因工程研究进展[J].安徽农业科学,2013,41(10):4273-4275. |
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| 作者姓名： | 王鑫 刘晖 沈玉娟 曹建平 |
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| 作者单位： | 遵义医学院寄生虫学教研室,贵州遵义,563003;中国疾病预防控制中心寄生虫病预防控制所,卫生部寄生虫病原与媒介生物学重点实验室,世界卫生组织疟疾、血吸虫病和丝虫病合作中心,上海200025 |
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| 基金项目： | 卫生部寄生虫病原与媒介生物学重点实验室开放课题 |
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| 摘 要： | 家蝇抗菌肽是家蝇体液免疫中的重要组成部分,是对细菌、病毒、真菌、肿瘤细胞和原虫均有抑制作用的小分子蛋白。随着细菌的耐药性和耐药菌株的出现,人们对家蝇抗菌肽的研究愈来愈关注,文中对家蝇抗菌肽的结构分类、生物学特性、表达调控和基因工程等方面进行了综述,并对其未来发展进行了展望。
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| 关 键 词： | 家蝇 抗菌肽 分类 生物学特性 基因工程 |
Research Advances in Antimicrobial Peptide of Musca domestica and Its Genetic Engineering |
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| Institution: | WANG Xin et al ( Department of Parasitology, Zunyi Medical College, Zunyi, Guizhou 563003 ) |
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| Abstract: | Antimicrobial peptide of Musca domestica is an important part of its humoral immunity and it is a class of small molecule protein which has a positive effect on bacteria, viruses, fungi, tumor cells and protozoa. With the appeararence of bacterial resistnace and drug-resistant strain, an increasing number of studies focus on antimicrobial peptide. The classification, biological characteristics, expression and regulation, fenetic engineering of antimierobial peptides were reviewed, the future development was forecasted. |
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| Keywords: | Musca domestica Antimicrobial peptide Classification Biological characteristics Genetic engineering |
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