| 内皮祖细胞生物学特性及其对改善新血管形成的影响 |
| |
| 引用本文： | 元虹懿,杜海荣,张明海.内皮祖细胞生物学特性及其对改善新血管形成的影响[J].农业科学与技术,2017,18(2). |
| |
| 作者姓名： | 元虹懿 杜海荣 张明海 |
| |
| 作者单位： | 东北林业大学野生动物资源学院,黑龙江哈尔滨,150040 |
| |
| 摘 要： | 内皮祖细胞(Endothelial progenitor ceils,EPCs)是可以直接分化为血管内皮细胞的一种前体细胞.当机体受到损伤、缺血或是在药物等外界因素刺激下都可动员骨髓内的内皮祖细胞参与到机体的内循环.内皮祖细胞可以通过旁分泌促血管生成因子来促进管腔直接进入发芽状态的新生血管来调节血管生成.该文综述了EPC的来源、分离培养、数量的影响因素及其对血管生成作用等几个方面.
|
| 关 键 词： | 内皮祖细胞 心肌梗死 血管新生 |
Biological Characteristics of Endothelial Progenitor Cell and Its Influence on Angiogenesis Improvement |
| |
| Hongyi YUAN,Hairong DU,Minghai ZHANG.Biological Characteristics of Endothelial Progenitor Cell and Its Influence on Angiogenesis Improvement[J].Agricultural Science ＆ Technology,2017,18(2). |
| |
| Authors: | Hongyi YUAN Hairong DU Minghai ZHANG |
| |
| Abstract: | Endothelial progenitor cell (EPC) is a term that refers to multiple cell types that play roles in the regeneration of the endothelial lining of blood vessels.The EPCs in bone marrow will participate in the internal circulation in a body subjected to the stimulation by external factors such as injury,ischemia or drug.EPCs regulate the angiogenic switch via paracrine secretion of proangiogenic growth factors and by direct luminal incorporation into sprouting nascent vessels.Therefore,this paper reviews the sources,isolation and culture of EPCs,the factors influencing the proliferation and activity of EPCs,and the roles of EPCs in angiogenesis. |
| |
| Keywords: | Endothelial progenitor cells Myocardial infarction Angiogenesis |
| 本文献已被 万方数据 等数据库收录！ |
|
