Horner's Syndrome Associated with Disseminated Thoracic Melanoma in a Lipizzaner Horse |
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Authors: | Sara Nannarone Marta Cercone Rodolfo Gialletti Marco Pepe |
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Institution: | 1. Veterinary Teaching Hospital, University of Perugia, Perugia, Italy;2. Department of Clinical Sciences, Cornell University, College of Veterinary Medicine, Ithaca, NY |
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Abstract: | A 20-year-old gelding Lipizzaner horse was referred for onset of profuse sweating and increased heat on the right side of the head, neck, and thoracic limb. On physical examination, the horse presented tachycardia, muffled heart sounds with a pansystolic murmur, and signs of heart failure such as ventral edema, jugular distention, and pulsation. Ultrasonography examination revealed a bilateral pleural effusion and a large intrathoracic mass extending into the anterior mediastinum, which shifted the heart dorsocaudally. Thoracocentesis revealed serosanguineous fluid indicative of a melanocytic tumor. Thoracoscopy revealed a large dark mass extending into and filling the cranioventral mediastinum. The mass appearance was consistent with a melanoma, and because prognosis was poor, the owner elected euthanasia. A necropsy supported the presence of disseminated melanomas with a greater thoracic mass involving the right cervicothoracic ganglion, leading to clinical signs of sympathetic denervation. |
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Keywords: | Equine Melanoma Cervicothoracic ganglion Sympathectomy Horner's syndrome |
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