Evaluation of Abdominal Fluid: Peripheral Blood Creatinine and Potassium Ratios for Diagnosis of Uroperitoneum in Dogs |
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Authors: | Chad Schmiedt DVM MS DACVS Karen M Tobias DVM MS DACVS Cynthia M Otto DVM phD DACVECC |
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Institution: | University of Tennessee, Department of Small Animal Clinical Sciences, Knoxville, TN (Schmiedt, Tobias) and the University of Pennsylvania, Department of Clinical Studies Philadelphia, PA |
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Abstract: | Objective: To determine the clinical efficacy of abdominal fluid to peripheral blood ratios of creatinine and potassium concentrations to diagnose uroperitoneum in dogs. Design: Records of 13 dogs with confirmed uroabdomen were retrospectively analyzed. Prospective evaluation of 8 dogs with nonrenal ascites provided data for a control population. Setting: Veterinary Medical Teaching Hospital. Animals: Client owned dogs. Interventions: None Measurements and Main Results: Abdominal fluid potassium (mEq/L) and creatinine concentrations (mg/dl) were recorded. Peripheral blood potassium and creatinine concentrations were also recorded. Ratios were calculated based on these values. An abdominal fluid creatinine concentration to peripheral blood creatinine concentration ratio of > 2:1 was predictive of uroabdomen in dogs (specificity 100%, sensitivity 86%). An abdominal fluid potassium concentration to peripheral blood potassium concentration of > 1.4:1 is also predictive of uroabdomen in dogs (specificity 100%, sensitivity 100%). All dogs with uroabdomen had an abdominal fluid creatinine concentration that was at least 4 times normal peripheral blood levels. Conclusion: Abdominal fluid to peripheral blood potassium and creatinine ratios provide a means to diagnose uroperitoneum in dogs without elevated peripheral blood creatinine. |
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Keywords: | ascites canine abdominocentesis bladder rupture diagnostic peritoneal lavage |
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