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育成公鸭硝基苯急性毒性试验
引用本文:王海波,杨本,邢厚娟,徐世文. 育成公鸭硝基苯急性毒性试验[J]. 东北农业大学学报, 2008, 39(9)
作者姓名:王海波  杨本  邢厚娟  徐世文
作者单位:东北农业大学动物医学学院,哈尔滨,150030
摘    要:本试验采用Weil′s平移法对金定育成公鸭进行硝基苯(NB)急性毒性试验。结果表明,NB对公鸭的经口急性中毒半数致死量(LD50)为447.20mg·kg-1BW,其可信区间为210.09-951.92mg·kg-1BW。急性中毒公鸭主要表现神经症状,剖检变化以腺胃胃壁增厚、黏膜脱落及肠道充血较明显。说明NB对公鸭具有较强的急性毒性作用。

关 键 词:硝基苯  公鸭  LD50

Effect of NB on acute toxicity in male duck
WANG Haibo,YANG Ben,XING Houjuan,XU Shiwen. Effect of NB on acute toxicity in male duck[J]. Journal of Northeast Agricultural University, 2008, 39(9)
Authors:WANG Haibo  YANG Ben  XING Houjuan  XU Shiwen
Affiliation:WANG Haibo,YANG Ben,XING Houjuan,XU Shiwen(College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China)
Abstract:The mean method of Weil′s table was used to determine the LD50 of the male duck induced by Nitrobenzene(NB). The results showed that the oral LD50 of the male duck induced by NB was 447.20 mg·kg-1 BW, the 95% confidence limit was 210.09-951.92 mg·kg-1 BW. The poisoned male ducks mainly showed nerves symptoms, the lesions were thickened stomach wall and sloughed mucosa of stomachus glandularis, and synathroi-sis of intestinal tract. The results indicate that NB has acute toxicity effect on the make duck.
Keywords:LD50
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