| 血根碱药理及毒理作用的研究进展 |
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| 引用本文： | 张乙涛,王慧. 血根碱药理及毒理作用的研究进展[J]. 中国畜牧兽医, 2012, 39(7): 214-217 |
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| 作者姓名： | 张乙涛 王慧 |
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| 作者单位： | 1. 山东省泗水县畜牧兽医站,山东泗水 273200;2. 山东省鲁南中药材资源开发工程技术研究中心,山东临沂 276005 |
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| 摘 要： | 血根碱(sanguinarine)作为一种苯菲啶异喹啉类生物碱,具有抗菌、抗炎、抗氧化、抗肿瘤、改善肝功能及诱导细胞凋亡等作用,同时对肝脏、心脏等具有一定的毒性。作者就血根碱对细菌、真菌和癌细胞的药理作用及毒性作一综述,为该药在临床中的有效合理应用奠定基础。
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| 关 键 词： | 血根碱 药理作用 毒理作用 |
| 收稿时间： | 2011-12-06 |
Research Progress on Effects of Sanguinarine on Pharmacology and Toxicology |
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| ZHANG Yi-tao , WANG Hui. Research Progress on Effects of Sanguinarine on Pharmacology and Toxicology[J]. China Animal Husbandry & Veterinary Medicine, 2012, 39(7): 214-217 |
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| Authors: | ZHANG Yi-tao WANG Hui |
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| Affiliation: | 1. Sishui Animal Husbandry and Veterinary Station, Sishui 273200,China;2. Shandong Research Center of Engineering and Technology for Development of Southern Chinese Herbal Medicine, Linyi 276005,China |
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| Abstract: | Sanguinarine as a benzene phenanthridine isoquinoline alkaloids with anti-bacterial, anti-inflammatory, antioxidant, antitumor,can improve liver function and induction of apoptosis and so on, while on the liver and heart has a certain toxicity. In this paper, it reviewed for the drug on bacteria, fungi and cancer cells pharmacological effects and toxicity, in order to lay the foundation for effective and rational application in clinic. |
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| Keywords: | sanguinarine pharmacological effects toxicological effects |
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