茶叶有效成分对黑色素形成的抑制作用

黑色素是一种高分子生物色素,皮肤的颜色由黑色素的合成类型、累积量、黑素小体的再分布及降解决定.太阳紫外线辐射是导致黑色素形成过多的最常见因素.黑色素虽能保护皮肤细胞免受紫外线损伤,但异常积累将会导致黑色素紊乱疾病的发生.因此开发绿色、安全、高效的植物来源的黑色素抑制剂成为近年来研究的热点.不少研究表明茶叶提取复合物或茶...

Inhibition of Active Compounds in Tea on Melanin Formation

Melanin is a kind of high molecular biological pigment.The color of skin is determined by the type and accumulation of melanin as well as the redistribution and degradation of melanosome.Solar ultraviolet radiation is the most common cause of melanin formation.Although melanin can protect skin cells from UV damage,the abnormal accumulation of melanin will lead to diseases related with melanin disorders.Therefore,the development of green,safe and efficient melanin inhibitors extracted from plants has become a research hotspot in recent years.Many studies have proved that extract or monomer compounds of tea could significantly inhibit(a)the activity of tyrosinase,(b)the growth,proliferation,infiltration and metastasis of melanocytes,(c)the occurrence of skin cancer.In this paper,the research progress of tea active compounds inhibiting melanin formation in acellular tyrosinase test system,cell test system,animal model and human skin was reviewed to fully explore the key active compounds,find a safe and efficient inhibitor of melanin synthesis and provide reference for the comprehensive utilization of tea products and increasing the added value of tea industry.