| 复合维生素脂质体的制备 |
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| 引用本文： | 井乐刚,赵新淮.复合维生素脂质体的制备[J].中国农学通报,2011,27(4):330-333. |
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| 作者姓名： | 井乐刚 赵新淮 |
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| 作者单位： | 1. 哈尔滨师范大学生命科学与技术学院,哈尔滨,150025
2. 东北农业大学乳品科学教育部重点实验室,哈尔滨,150030 |
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| 基金项目： | 黑龙江省青年科学基金项目，黑龙江省教育厅科学技术研究项目，哈尔滨师范大学博士科研启动基金项目 |
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| 摘 要： | 以大豆粉末磷脂为壁材，以盐酸硫胺素（维生素B1）、核黄素（维生素B2）、盐酸吡哆醇（维生素B 6）、叶酸、烟酰胺的混合物为芯材，采用冷冻干燥-粉碎-筛分工艺，制备了复合维生素脂质体，考察了壁材/芯材比对脂质体中维生素荷载量及包埋率的影响。结果表明，随着壁材/芯材比的增加，维生素的包埋率增加而荷载量降低，比较合适的壁材/芯材比为15:1（w/w）。
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| 关 键 词： | 脂质体 复合维生素 制备 大豆磷脂 |
| 收稿时间： | 2010/11/1 0:00:00 |
| 修稿时间： | 2010/12/8 0:00:00 |
Preparation of Compound Vitamin Liposomes |
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| Jing Legang,Zhao Xinhuai.Preparation of Compound Vitamin Liposomes[J].Chinese Agricultural Science Bulletin,2011,27(4):330-333. |
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| Authors: | Jing Legang Zhao Xinhuai |
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| Institution: | Jing Legang1,Zhao Xinhuai2(1College of Life Science and Technology,Harbin Normal University,Harbin 150025,2Key Laboratory of Dairy Science,Ministry of Education,Northeast Agricultural University,Harbin 150030) |
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| Abstract: | In order to mask off-flavor and enhance stability of vitamins,compound vitamin liposomes were prepared by freeze-drying-comminuting-sieving.Soybean phospholipid powder was selected as coating material.The mixture of thiamine hydrochloride,riboflavin,pyridoxine hydrochloride,folic acid and nicotinamide was used as core material.Influences of ratio of coating material to core material on the loading and encapsulation efficiency of vitamins in liposomes were investigated.Results indicated that as the ratio of ... |
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| Keywords: | liposome compound vitamin preparation soybean phospholipid |
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