| 帕金森病营养防治研究进展 |
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| 引用本文： | 刘昌盛,肖冰,吕淑霞.帕金森病营养防治研究进展[J].安徽农业科学,2006,34(11):2621-2622. |
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| 作者姓名： | 刘昌盛 肖冰 吕淑霞 |
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| 作者单位： | 沈阳农业大学生物科技学院,辽宁,沈阳,110161 |
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| 基金项目： | 刘健康老师对本文的悉心指导. |
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| 摘 要： | 由营养缺乏或环境损伤等因素引起的氧化损伤所导致的线粒体衰退是帕金森病的早期事件。在体外实验和动物模型上的研究发现,一些营养物可以通过针对线粒体衰退而改善线粒体功能,从而预防和治疗帕金森病。这些营养物包括:叶酸、辅酶Q10、乙酰左旋肉碱、NAD/NADH、硫辛酸、核黄素及各种维生素等,其中有些已在临床试验中表现出良好的应用前景。
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| 关 键 词： | 线粒体衰退 营养物 帕金森病 |
| 文章编号： | 0517-6611（2006）11-2621-02 |
| 收稿时间： | 2006-04-05 |
| 修稿时间： | 2006-04-05 |
Evolution of Study on Prenentment and Ameliopate Parkinson's Disease by Nutrients |
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| LIU Chang-sheng et al.Evolution of Study on Prenentment and Ameliopate Parkinson''''s Disease by Nutrients[J].Journal of Anhui Agricultural Sciences,2006,34(11):2621-2622. |
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| Authors: | LIU Chang-sheng |
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| Institution: | College of Biological Science and Technology, Shenyang Agricultural University, Shenyang,Liaoning 110161 |
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| Abstract: | Mitochondrial decay due to oxidative damage by environmental insults or nutrient deficient is a key contributor to Parkinson's disease(PD).It is suggested that some nutrients can prevent and ameliorate PD by targeting mitochondrial decay with nutrients,whose deficiency causes mitochondrial dysfunction and supplementation improves mitochondrial function.These nutrients include Folic acid,coenzyme Q10,acetyl-L-carnitine,NAD /NADH,lipoic acid,riboflavin and various vitamins.Some of them have shown promising effects in clinical trials. |
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| Keywords: | Mitochondria dysfunction Nutrients Parkinson's disease |
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