Successful treatment of mandibular squamous cell carcinoma in a Malayan sun bear (Helarctos malayanus). |
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Authors: | Natalie D Mylniczenko Ann L Manharth Leigh Ann Clayton Rhonda Feinmehl Mitch Robbins |
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Affiliation: | Lincoln Park Zoo, 2001 North Clark Street, Chicago, Illinois 60614, USA. |
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Abstract: | An adult, female Malayan sun bear (Helarctos malayanus) was diagnosed with squamous cell carcinoma of the rostral mandible. Initial treatment included bilateral mandibulectomy rostral to the lingual frenulum followed by intra- and perilesional cisplatin injections. Recovery after the procedure was uneventful and the Malayan sun bear adapted well to a shortened mandible. Histopathology indicated incomplete surgical excision of the tumor; therefore, radiation therapy was instituted weekly for four treatments at 2 Gy in parallel opposed fields (total 4 Gy each treatment) with one additional cisplatin treatment. Two years after initial presentation, the animal showed no recurrence of neoplasia. |
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