鹿茸保健饮品对氢化可的松所致小鼠肾阳虚症的影响

目的评定鹿茸保健饮品对氢化可的松所致小鼠肾阳虚症的影响。方法将小鼠分为氢化可松所致肾阳虚小鼠模型组及鹿茸保健饮品低剂量、中剂量、高剂量3个剂量组。每天灌胃生理盐水及鹿茸保健饮品1次,连续28d。分别以体重、生殖脏器指数、负重力竭游泳时间和血清、肾脏中一氧化氮含量为指标,观察鹿茸保健饮品对肾阳虚小鼠的作用效果。结果与模型组比较,鹿茸保健饮品各剂量组小鼠的体重明显增加（P〈0.05）;小鼠睾丸、睾丸-附睾、精液囊-前列腺的指数明显增加（P〈0.05）;负重游泳时间明显延长（P〈0.05）;运动后血清和肾组织中一氧化氮的含量明显升高（P〈0.05）。结论该鹿茸保健饮品具有促进性腺、附性腺的生长及补肾作用,同时具有明显的抗疲劳功效。

Effects of Health Velvet Drink on the Kidney-yang Deficiency Syndrome in Mice induced by administering Hydrocortisone

Objective To observe the effects of health velvet drink on mice with kidney-yang deficiency which was induced by hydrocortisone.Methods The mice were randomly divided into 4 groups based on the dosage of the drink, model of hydrocortisone-induced kid-ney-yang deficiency group, low-dose group, middle-dose group, high-dose group.The mice were filled stomach once a day, for 28consecutive days.It was assayed that weight and growth of sex organs, weight-bearing swimming time and the content of nitric oxide in serum and kidney in the end of the experiment.Result Comparing with model group, body weight, weight of testis and prostate-sperm sac , and the content of nitric oxide in serum and kidney of experimental groups were significantly improved（P 〈0.05）, and weight-bearing swimming time was significantly longe（rP 〈0.05）.Conclusion The results suggested that health velvet drink had tonic effects on gonad growth, kid-ney-nourishing function and with a clear antifatigue effect.