Seroconversion of anti-Getah virus antibody among Japanese native Noma horses
around 2012 |
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| Authors: | Makoto TAKEISHI Ryusei KUWATA Tetsushi ONO Asami SASAKI Mone OGATA Eri IWATA Syuichi TAJI Masamitsu KOIKE Manabu NEMOTO Hiroshi BANNAI Haruhiko ISAWA Ken MAEDA Shigeru MORIKAWA Hitoshi KITAGAWA Yasuhiro YOSHIKAWA |
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| Affiliation: | 1)Faculty of Veterinary Medicine, Okayama University of Science, Ehime, Japan;2)Toyo Livestock Hygiene Service Center Imabari Branch Office in Ehime, Ehime, Japan;3)Equine Research Institute, Japan Racing Association, Tochigi, Japan;4)Department of Medical Entomology, National Institute of Infectious Diseases, Tokyo, Japan;5)Department of Veterinary Science, National Institute of Infectious Diseases, Tokyo, Japan |
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| Abstract: | Getah virus (GETV), an arthropod-borne virus transmitted by mosquitoes, has been isolated from several animals. GETV infection in horses shows clinical signs such as fever, rash, and edema in the leg. Noma horses are one of the eight Japanese native horses. The present study aimed to clarify the occurrence of GETV infection in Noma horses. Serum samples collected from Noma horses were analyzed using a virus neutralization test and enzyme-linked immunosorbent assay and showed that the anti-GETV antibody titers in the samples collected in 2017 were significantly higher than those collected in 2012. We concluded that a seroconversion of anti-GETV antibodies was occurred in the Noma horse population around 2012, providing evidence of the GETV epidemic in Japan circa 2012. |
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| Keywords: | ELISA Getah virus Japanese native horse virus neutralization test |
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