Electroretinographic study of the white mouse intoxicated by organophosphorus: Methylparathion,parathion, and paraoxon |
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Authors: | Pierre Carricaburu Roger Lacroix Josyane Lacroix |
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Institution: | 1. Laboratoire de biophysique, Faculté de médecine, BP V 166 Abidjan, Ivory Coast;2. Laboratoire de pharmacie chimique, Faculté de pharmacie, 2 bis, boulevard Tonnellé, F-37032 Tours Cedex, France |
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Abstract: | Methylparathion, parathion, and paraoxon have an almost identical influence on the electrical ocular response of the white mouse: action on the photoreceptors, synaptolytic effect, and possible damage of the bipolar neurons. However, methylparathion and parathion can be differentiated from paraoxon by their immediate action on the photoreceptors, action which might result from the presence of sulfur in their molecular structure. |
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