颗粒细胞对卵泡发育的影响

卵泡发育是一个复杂的生理过程，通过间隙连接，颗粒细胞在卵母细胞的生长发育过程中起营养作用，并促进卵母细胞的成熟；颗粒细胞和膜细胞的相互作用是卵泡发育和维持正常功能的重要条件。作为卵泡发育的标志，颗粒细胞的生长分化是原始卵泡启动和生长的关键，并通过受体介导途径调控生长期卵泡的发育及卵泡闭锁，从而在卵泡发育过程中起重要的调控作用。

Effect of Granulosa Cells on Follicle Development

Follicle development is a complicated physiological process. Granulosa cells,by means of gap junctions, allow the transfer of the oocyte metabolic needs and promote the maturation of the oocyte. The interactions between granulosa cells and thecal cells play an indispensable role in follicle development and maintaining follicle’s normal function. As a symbol of follicle development, the growth and differentiation of the granulose cells play an important role in initiation and growth of primordial follicle. Also,granulosa cells regulate the follicle development artesia via receptor-mediated means and play an important role in the regulation of follicle development.