Paramunization of FeLV-positive cats with PIND-AVI]

84 FeLV-positive cats were continually treated with the paramunity inducer (immunomodulator) PIND-AVI (23 healthy cats once a week, 61 diseased cats up to 3 times a week), the frequency depending on their general condition. The ELISA control tests were repeated after 4 to 6 weeks. Paramunization was continued in cats still viremic until remission of viremia. 21 healthy cats already reacted negatively to the first control ELISA, the 2 others after 8 weeks of paramunization. Within an observation time of 18 to 30 months there were no relapses. 49 of the 61 diseased cats (80.3%) reacted negatively to the first control. 5 cats (8.2%) had died at the beginning of the treatment. 5 cats (8.2%) showed a remission of viremic after being paramunized continually for 7 to 20 weeks. 2 cats (3.3%) remained viremic throughout the observation time (more than 2 years). None of the animals had a relapse. Neither had any of 9 chronically diseased cats, known to have been viremic for 3 to 12 months at the beginning of paramunization. The importance of the results of these paramunization tests for the treatment of various retrovirus infections of human beings and animals is briefly discussed.