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Diabetic retinopathy in a cat with megestrol acetate-induced diabetes
Authors:M. E. HERRTAGE,K. C. BARNETT,D. F. MACDOUGALL &dagger  
Affiliation:Department of Clinical Veterinary Medicine, Madingley Road, Cambridge CB3 OES;*Comparative Ophthalmology Unit, The Animal Health Trust, Lanwades Park, Kennett, Newmarket, CB8 7PN;**Renal Unit, The Animal Health Trust, Lanwades Park, Kennett, Newmarket, CB8 7PN
Abstract:A case of diabetes mellitus in a cat is described, associated with prolonged administration of megestrol acetate for miliary dermatitis. The cat was presented with blindness due to diabetic retinopathy. Following the diagnosis, megestrol acetate was withdrawn. The diabetes proved to be transient and resolved after insulin therapy; however, severe visual impairment remained. The mechanism by which megestrol acetate induces diabetes is discussed.
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