| 噬菌体及其内溶素的应用研究进展 |
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| 引用本文： | 刘伟,王学琴,董世雷,朱立颖,王欣. 噬菌体及其内溶素的应用研究进展[J]. 浙江农业学报, 2010, 22(5): 702 |
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| 作者姓名： | 刘伟 王学琴 董世雷 朱立颖 王欣 |
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| 作者单位： | 1.浙江省农业科学院 植物保护与微生物研究所,浙江 杭州 310021;2.内蒙古工业大学 化工学院,内蒙古 呼和浩特 010051;3.浙江师范大学 化学与生命科学学院,浙江 金华 321004 |
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| 摘 要： | 抗生素的滥用使越来越多的病原菌产生抗药性,因此寻求新的抗菌素已经变得极为迫切。噬菌体以及噬菌体编码的内溶素的发现和应用,为耐药性细菌的治疗和预防开辟了新的途径。文章综述了近几年噬菌体和内溶素的研究进展及其应用。
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| 关 键 词： | 内溶素 抗性 噬菌体 病原菌 |
Advances in research and development of phage and phage-encoding lysins |
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| LIU Wei,WANG Xue-qin,DONG Shi-lei,ZHU Li-ying,WANG Xin. Advances in research and development of phage and phage-encoding lysins[J]. Acta Agriculturae Zhejiangensis, 2010, 22(5): 702 |
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| Authors: | LIU Wei WANG Xue-qin DONG Shi-lei ZHU Li-ying WANG Xin |
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| Affiliation: | 1Institute of Plant Protection and Microbiology, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China; 2College of Chemical Engineering, Inner Mongolia University of Technology, Hohhot 010051, China; 3College of Chemistry and Life Science, Zhejiang Normal Univeristy, Jinhua 321004, China |
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| Abstract: | With the widespread resistance to antibiotics among pathogenic bacteria, it is particularly urgent to develop new antibiotic alternatives. Extensive studies have shown that phage and phage-encoded lytic enzymes (virolysins) were two of the most promising alternative antibacterials for the treatment and prophylaxis of bacterial infections. This review was focused on the recent advance of research and development and related applications in phage and lysins． |
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| Keywords: | virolysin antibiotic resistance phage pathogen |
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