Mapping and investigation of the porcine major insulin sensitive glucose transport (SLC2A4/GLUT4) gene as a candidate gene for meat quality and carcass traits |
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| Authors: | E. GRINDFLEK,,R. HOLZBAUER,,G. PLASTOW, & M. F. ROTHSCHILD |
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| Affiliation: | Department of Animal Science, Agricultural University of Norway, Norway,;The Norwegian Pig Breeders Association, Norway,;PIC Group Fyfield Wick, Abingdon, Oxfordshire, UK,;Department of Animal Science, Iowa State University, Ames, USA |
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| Abstract: | The porcine major insulin sensitive glucose transport gene (known by SLC2A4 and GLUT4 ) was mapped, by physical and linkage methods, to chromosome 12 in the PiGMaP population. Furthermore, the role of the porcine SLC2A4 was investigated in about 1700 animals from different pig breeds and crosses from the USA and Norway. Ten traits for meat quality and carcass composition were recorded for the U.S. population, while 44 traits for meat quality traits were recorded for the Norwegian population. For the analyses of associations between SLC2A4 gene variants and quantitative traits, one restriction fragment length polymorphism (RFLP) was examined. Relatively weak and inconsistent associations were found in some of the lines investigated between SLC2A4 genotypes and the meat quality traits drip loss, colour, loin marbling and loin depth (p < 0.05). Due to the inconsistencies in the results we conclude that it is likely that the SLC2A4 polymorphism investigated is not associated with meat quality traits in the lines studied. |
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