"神蜂"牌J9311蜂胶囊抗癌作用试验研究

以J931 1蜂胶囊水溶液为样品 ,对小鼠进行了抑制S1 80 实体瘤 (小鼠肉瘤细胞系 )和H2 2 实体瘤 (小鼠肝癌细胞系 )试验以及成分合理性分析试验。试验结果显示 ,对于S1 80 实体瘤 ,J931 1蜂胶囊的有效抑瘤剂量范围是 :0 6g kg～ 4 8g kg。以0 3g kg、0 6g kg、1 2g kg为低、中、高剂量进行抑瘤试验显示 ,中、高剂量组小鼠瘤重明显降低 ,与对照组比较差异显著 (P <0 0 5 ,P <0 0 1 ) ;对于H2 2 实体瘤的有效抑瘤剂量范围是 :1 6g kg～ 6 0g kg ,重复试验差异性结果与S1 80 实体瘤相同。结果表明J931 1蜂胶囊具有抑制小鼠S1 80 和H2 2 实体瘤的作用。J931 1蜂胶囊成分合理性试验显示 ,J931 1蜂胶囊组分抑瘤效果显著优于单独成分及各成分二二组合 ,单独成分中蜂王浆和蜂胶起主要抑瘤作用 ,中药成分起辅助作用

Study on the Anti-tumor Effect of "Shen Feng" J9311 Propolis Capsule

In this study, the water solution of J9311Propolis Capsule was used to test the anti_tumor effect on S 180 and H 22 tumor cells. Also the components analysis was carried out. Anti_tumor experiment result has shown that the effective dosage range of J9311 propolis capsule for S 180 is from 0.6g/kg to 4 8g/kg. In comparison with the control group, the anti_tumor rate of the median group has significant difference and the high one bas very significant difference. As for H 22 , the range (1 6g/kg to 6 0g/kg), the dosage (low 0 8g/kg,median 1 6 g/kg, high 3 2g/kg) and the inhibiting tumor rate among three groups are quite similar to S 180 test, and the difference result also is the same as S 180 test. Analysis of ingredients combination of J9311 has proved that royal jelly and propolis have obvious effect, and the Chinese herb has supplementary effect in inhibiting S 180 tumor.