| 播散性皮层抑制猫脑模型及MRI成像平面的研究 |
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| 引用本文： | 任伯绪,蔡新宇,黄劲柏,陈昌毅,雷红卫. 播散性皮层抑制猫脑模型及MRI成像平面的研究[J]. 长江大学学报, 2009, 6(1) |
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| 作者姓名： | 任伯绪 蔡新宇 黄劲柏 陈昌毅 雷红卫 |
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| 作者单位： | [1]长江大学医学院,湖北荆州434023 [2]长江大学附属第一医院荆州市第一人民医院放射科,湖北荆州434000 |
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| 基金项目： | 湖北省卫生厅科研基金项目(JX3B73) |
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| 摘 要： | 目的：建立播散性皮层抑制的猫脑模型，寻找合适的MRI成像平面。方法：雌猫6只，双侧额窦开颅并充填以琼脂糖凝胶，双侧上侧裂回上方开颅，以备注入氯化钾凝胶。MRI检查行垂直相交的高分辨力横断面、矢状面及冠状面T1WI，研究各方位图像显示脑回的解剖特点，然后分别行静患期、氯化钾刺激期fMRI检查。结果：双侧额窦均充填良好；横断面图像仅能显示嘴尾侧走行脑回的一个断面；矢状面不能显示相邻脑回间的关系；包括双侧上侧裂回和边缘回的冠状面图像既能显示脑回的长轴，又能显示相邻脑回的关系，且能提供对侧大脑半球作为对照。fMRI显示氯化钾刺激区上侧裂回及邻近边缘回脑皮层可见脑功能激活区者5例，并播及到同侧边缘回后部。结论：双侧额窦充填能改善图像质量；上侧裂回是研究播散性皮层抑制最合适的皮层结构；包括双侧上侧裂回和边缘回的冠状面是磁共振功能成像研究播散性皮层抑制的理想成像层面。
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| 关 键 词： | 播散性皮层抑制 磁共振成像 猫 解剖 |
Study of Cat Model for Spreading Cortical Depression and the Plane of Magnetic Resonance Imaging |
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| REN Bo-xu,CAI Xing-yu,HUANG Jin-bai CHENG Cang-yi,LEI Hong-wei. Study of Cat Model for Spreading Cortical Depression and the Plane of Magnetic Resonance Imaging[J]. Journal of Yangtze University, 2009, 6(1) |
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| Authors: | REN Bo-xu CAI Xing-yu HUANG Jin-bai CHENG Cang-yi LEI Hong-wei |
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| Affiliation: | Medical School of Yangtze University;Jingzhou 434023;China;X-ray department;the First Hospital of Yangtze University;Jingzhou 434000;China |
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| Abstract: | Objective:To establish cat model for spreading cortical depression and explore appropriate plane on magnetic resonance imaging.Methods:Craniotomies were performed in both orbital sinuses and the sinuses were filled with agar.Craniotomies over the suprasylvian gyri and durectomy exposed the surface of suprasylvian gyri for the injection of KCl/agar solution.The anatomical images included high-resolution T1W images covering the whole brain in vertical transverse,sagittal and coronal planes.The anatomic charac... |
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| Keywords: | Spreading cortical depression Magnetic resonance imaging Cats Anatomy |
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