| Abstract: | Vaccination schedules and a challenge carried out in laboratory animals are necessary to test the Rabies vaccines for potency.Two main techniques, described by W.H.O., are compared:—The Habel test is a system involving a constant vaccine and a variable virus.—The N.I.H. test is the inverse system with a few major differences during the immunization phase.Although the Habel test is easier to implement, it is quite impossible to make a rigourous statistical interpretation of its results.Although it is more difficult to implement the N.I.H. test as it requires a reference vaccine and a titrated viral suspension, the statistical interpretation is simple.For a same vaccine, the variation amplitude is 1 to 250 for the Habel test and 1 to 7,6 for the N.I.H. test. The N.I.H. test is preferred to the Habel test |
