绵羊肺炎支原体分子致病机理研究进展

绵羊肺炎支原体（Mycoplasma ovipneumoniae,MO）引起的支原体肺炎（Mycoplasma pneumonia）是严重危害养羊业的重要呼吸道疫病。绵羊肺炎支原体感染具有隐蔽性、持续性,造成患病羊生产性能下降,严重影响养羊经济效益。综合近期国内外关于绵羊肺炎支原体分子致病机制的文献报道,从绵羊肺炎支原体与呼吸道上皮细胞黏附、致下呼吸道损伤和引起机体免疫抑制三方面进行综述,以期为后续深入研究绵羊肺炎支原体致病机理、开发新型防控技术奠定基础。

Research Progress in Molecular Pathogenic Mechanism of Mycoplasma ovipneumoniae

Mycoplasma pneumonia caused by Mycoplasma ovipneumoniae （MO） is a devastating respiratory disease that puts the sheep industry at risk. MO infection is often insidious and persistent, resulting in reduced productive performance of diseased sheep and serious economic losses in sheep industry. By consulting the recent literature on molecular pathogenic mechanism of MO in China and abroad, we render a review from the following three aspects of adhesion of MO to respiratory epithelial cells, lower respiratory tract injuries caused by MO, and immune suppression induced by MO, in hoping to lay the groundwork for a more in-depth investigation on pathogenic mechanism of MO and for the development of innovative preventative and control strategies.