边界病的研究进展

边界病（border disease,BD）是由边界病病毒（border disease virus,BDV）引起绵羊和山羊感染的一种传染性疾病,在世界范围内给畜牧业生产造成巨大的经济损失。该病临床表现为母羊生殖障碍,羔羊畸形、震颤、多毛等。BDV在绵羊、牛和猪的种间传播经常发生,给该病的诊断带来困难。目前,尚无有效的疫苗用于边界病的防控,因此,了解不同区域的边界病流行情况有助于防止其传播并优化控制措施。结合国内外近期研究报道,从病原学、流行病学、诊断措施等方面对边界病进行综述,以期为该病的防控工作提供参考。

Research Progress on Border Disease

Border disease （BD）, caused by border disease virus （BDV）, is an infectious disease in sheep and goats. This disease brings massive economic losses in livestock production around the world. BDV infection causes reproductive disorders in ewes and deformity, tremor, hairiness in lambs. Interspecies transmission of BDV among sheep, cattle and pigs frequently occurs, posing challenges in diagnosis of BD. There is currently no available vaccines for BD prevention and control. Understanding the prevalence of BD in different geographical regions can thus aid in the prevention of transmission and the optimization of control measures of this disease. Based on the current research, this paper reviews BD from the perspectives of etiology, epidemiology, and diagnostic measures, in hoping to provide a reference for the prevention and control of this disease.