改善早期断奶仔猪肠道健康和功能的营养策略研究进展

商业化生产中仔猪早期断奶（3~4周龄）恰是肠道功能发育的关键时期,断奶应激带来的持续性肠道屏障功能损伤是断奶仔猪细菌性和病毒性肠炎及断奶后腹泻的主要诱因。饲料端“禁抗”背景下,运用营养策略改善早期断奶仔猪肠道功能的研究是研究者关注的焦点问题。从早期断奶对仔猪肠道屏障功能的影响及多种营养策略对断奶仔猪肠道功能改善的作用,综述了早期断奶致仔猪肠道屏障功能损伤的机理及氨基酸、抗菌肽、益生菌、膳食纤维、低聚糖、有机酸、微量营养素和脂质营养等营养策略改善仔猪肠道功能的作用机制,为通过营养策略改善断奶仔猪肠道功能相关研究提供参考。

Advances in Nutritional Strategies for Improvement of Intestinal Health and Function in Early Weaned Piglets

In commercial swine production, the early weaning stage of piglets （3-4 weeks of age） is the key period of intestinal function development. Weaning stress is primarily responsible for the continuous intestinal barrier function deterioration that results in bacterial and viral enteritis, as well as post-weaning diarrhea in weaned piglets. Under the background of 'antibiotic-free' in the feed end, researchers are focusing on adopting nutritional approaches to enhance the intestinal function of early weaned pigs. In this paper, the underlying mechanisms of intestinal barrier function damage caused by early weaning and those of improving intestinal function of piglets by nutritional strategies such as amino acids, antimicrobial peptides, probiotics, dietary fiber, oligosaccharides, organic acids, micro-nutrients, and lipid nutrition were reviewed in relation to the affects of early weaning on the intestinal barrier function of piglets and the impacts of various nutritional strategies on the improvement of intestinal barrier function of weaned piglets, in hoping to provide references for the research on improving the intestinal function of weaned piglets through nutritional strategy.