Histological Changes in the Deep Branch of the Lateral Palmar Nerve of Horses With Induced Proximal Suspensory Desmitis |
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| Affiliation: | 1. Departamento de Medicina y Zootecnia de Equidos, Facultad de Medicina Veterinaria y Zootecnia, UNAM Mexico, Ciudad de Mexico, Mexico;2. Departamento de Patologia, Facultad de Medicina Veterinaria y Zootecnia, UNAM Mexico, Ciudad de Mexico, Mexico;3. Departamento de Biologia Celular y Fisiologia, Instituto de Investigaciones Biomedicas, UNAM Mexico, Ciudad de Mexico, Mexico;4. Department of Clinical Science, College of Veterinary Medicine, Auburn University, Auburn, AL;5. Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN;1. Odisee Brussel, Educational Department of Medical Imaging Technologists (BE), Brussel, Belgium;2. Animal Health Trust, Newmarket (U.K.), Newmarket, Suffolk, UK;3. Department of Radiology, University Hospital Brussels (UZ Brussel), Brussels, Belgium;4. Faculté de Médecine Vétérinaire de l’Université de Liège, Service d''imagerie, Liège (Sart Tilman), Belgium;1. Hokkaido South Agricultural Mutual Aid Association Mitsuishi Animal Medical Center, Hidaka-gun, Hokkaido, Japan;2. Federation of Hokkaido Agricultural Mutual Aid Associations, Large Animal Clinic and Research Center, Ebetsu, Hokkaido, Japan;1. Faculty of Health and Medical Sciences, Department of Veterinary Clinical Sciences, University of Copenhagen, Taastrup, Denmark;2. School of Veterinary Medicine, Department of Clinical Studies-NBC, University of Pennsylvania, Kennett Square, PA;1. Programa de Pós-Graduação em Zootecnia, Universidade Federal de Pelotas, Pelotas, RS, Brazil;2. Departamento de Morfologia, Instituto de Biologia, Universidade Federal de Pelotas, Pelotas, RS, Brazil;3. Departamento de Veterinária Preventiva, Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas, RS, Brazil;4. Departamento de Clínicas Veterinária, Faculdade de Veterinária, Universidade Federal de Pelotas, Pelotas, RS, Brazil |
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| Abstract: | Desmitis of the proximal aspect of the suspensory ligament, or interosseus medius muscle, of the pelvic or thoracic limb is a commonly diagnosed cause of lameness of performance horses. Despite medical treatments available for horses with proximal suspensory desmitis (PSD), most horses treated medically for PSD of a pelvic limb remain persistently lame; this persistent lameness may be the result of a neuropathy caused by compression of nerves by an enlarged suspensory ligament. Few horses with PSD of a thoracic limb remain persistently lame. Based on the results of reports citing successful treatment of horses chronically lame because of PSD of a pelvic or thoracic limb, by excising a portion of the deep branch of the lateral plantar or palmar nerve (DBLPlN/DBLPaN), we theorized that persistent lameness of horses caused by PSD of a thoracic limb may also be due to compression of nerves that supply the ligament. The aim of this study was to determine if histological signs of compression neuropathy of the DBLPaN are present in horses with PSD in a thoracic limb. To test this hypothesis, we induced PSD by instilling collagenase into the ligament and then examined the DBLPaN after harvesting this nerve 2 months later. We found that the DBLPaNs of all treated limbs showed histologic changes suggestive of nerve compression. We conclude that studies examining the DBLPaN of horses with naturally occurring PSD for histological evidence of neuropathy are warranted. |
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| Keywords: | Horses Proximal suspensory desmitis Nerve degeneration |
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