A new hepoprotective saponin from Semen Celosia cristatae |
| |
| Authors: | Sun Zhen-Liang Gao Gang-Long Xia Yin-Fang Feng Jing Qiao Zeng-Yong |
| |
| Institution: | a Branch Hospital in Fengxian of Shanghai No 6 People's Hospital, 9588 NanFeng Road, Shanghai 201400, PR China |
| |
| Abstract: | A new triterpenoid saponin, named semenoside A (1), was isolated from Semen Celosia cristatae. Its structure was elucidated on the basis of 1D, 2D NMR, HR-FAB-MS and ESI-MS techniques, and physicochemical properties. The hepatoprotective activity of semenoside A with an oral dose of 1.0, 2.0 and 4.0 mg/kg, respectively, were investigated by carbon tetrachloride (CCl4)-induced hepatotoxicity in mice. The results indicated that it had significant hepatoprotective effects (p < 0.01). |
| |
| Keywords: | Semen Celosia cristatae Semenoside A Hepatoprotective effect |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
