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牛病毒性腹泻BVDV2/JZ05-1基础毒株的安全性和免疫原性研究
引用本文:李海涛,苗利光,刘艳环,朱言柱,王松,王文昊,安亚.牛病毒性腹泻BVDV2/JZ05-1基础毒株的安全性和免疫原性研究[J].特产研究,2012(2):5-8.
作者姓名:李海涛  苗利光  刘艳环  朱言柱  王松  王文昊  安亚
作者单位:中国农业科学院特产研究所,吉林吉林132109
基金项目:吉林省科技发展计划(20100219)
摘    要:本试验用已分离到的牛病毒性腹泻病毒BVDV2/JZ05-1基础毒株对犊牛免疫的安全性和免疫原性进行了研究。通过对基础毒种单剂量、超剂量、单剂量重复安全试验和免疫原性试验研究证实,BVDV2/JZ05-1对犊牛免疫是安全的,对犊牛感染BVDV有很好的免疫保护效果。

关 键 词:牛病毒性腹泻  安全性试验  免疫原性试验

Safety and Immunogenicity Study of Bovine Viral Diarrhea Virus 2 Strain JZ05-1
LI Hai-tao,MIAO Li-guang,LIU Yan-huan,ZHU Yan-zhu,WANG Song,WANGWen-hao,AN Ya-xiong.Safety and Immunogenicity Study of Bovine Viral Diarrhea Virus 2 Strain JZ05-1[J].Special Wild Economic Animal and Plant Research,2012(2):5-8.
Authors:LI Hai-tao  MIAO Li-guang  LIU Yan-huan  ZHU Yan-zhu  WANG Song  WANGWen-hao  AN Ya-xiong
Institution:(Institute of Special Wild Economic Animals and Plants,CAAS,Jilin 132109,China)
Abstract:The bovine viral diarrhea virus 2 strain JZ05-1(BVDV2/JZ05-1) was isolated in this experiment.Single dose,overdose and single dose reduplication safety experiment and immunogenicity experiment were carried out in this experiment.When the calves were immunized with BVDV2/JZ05-1,the safety and immunogenicity of BVDV2/JZ05-1 were examined.The results suggested that the immunization of BVDV2/JZ05-1 is safe for calves,and it can well protect calves from the BVDV.
Keywords:Bovine viral diarrhea  Security test  Immunogenicity test
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