意大利蜂工蜂幼虫和蛹的药理作用初探

从抗肿瘤、抗衰老、调节机体免疫功能三方面对工蜂幼虫、蛹的药理作用进行了研究，结果表 明，工蜂幼虫、蛹对小鼠Ｓ１８０肿瘤生长有明显的抑制作用，其抑瘤率分别达６０．９２％和６４．３７％，荷瘤小鼠的生命延长率分别达８０． ６５％和８１． ７４％；工蜂幼虫、蛹能提高大鼠脑、肝脏和血液中ＳＯＤ的活性，降低ＭＤＡ的含量，提高小鼠脑组织中ＲＮＡ和蛋白质的含量；工蜂幼虫、蛹能提高小鼠Ｔ淋巴细胞转化功能、碳廓清指数和胸腺指数，具有提高机体的细胞免疫和非特异性免疫功能的作用，工蜂幼虫、蛹的药理作用与蜂王幼虫相比，差异不显著。

Study on pharmacologic action of worker bee larvae and pupae of Italian Bee(Apis mellifera ligustica)

Study on pharmacologic action of worker bee larvae and pupae of Italian Bee (Apis mellifera ligustica was carried out in 3 aspects :antitumor , antiagting , regulation of immunity function. The results showed that the worker bee larvae and pupae had evident inhibitive effect on S180 tumor growth. The in- hibiting tumor rates were 60. 92% and 64. 37% respectively, and the prolonging longetive rates were 80. 65 % and 81. 74 % respectively ; The worker bee larvae and pupae sigiuficantly increased the SOD activi- ties and reduce the contents of MDA of brain, liver and blood of rats, while significantly increased RNA and protein contents in brain tissue of mice ;The worker bee larvae and pupae can significantly increase T- lymphocyte transformation function , charcoal clearance index and thymus index , and had obvious effect of cell-mediated immunity and unspeific immunity. No significant difference existed between worker bee lar- vae , pupae and queen bee larvae.