| N—甲基—D，L—天冬氨酸（NMA）对育肥猪生长激素基因表达的影响 |
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| 引用本文： | 许梓荣,卢建军,肖平. N—甲基—D，L—天冬氨酸（NMA）对育肥猪生长激素基因表达的影响[J]. 中国兽医学报, 2001, 21(6): 631-633 |
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| 作者姓名： | 许梓荣 卢建军 肖平 |
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| 作者单位： | 浙江大学饲料科学研究所农业部动物营养与饲料重点实验室,浙江,杭州,310029 |
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| 基金项目： | 国家自然科学基金重大资助项目(39870593) |
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| 摘 要： | 以肥育猪为对象，探讨了日粮中添加50mg/kgN－甲基－D，L－天冬氨酸（NMA）对其生长激素（GH）基因表达的影响。结果表明，添加NMA后，肥育猪日增重提高了9．31％（P＜0．01）；料重比降低了7．16％（P＜0．02）；血清GH含量提高了92．54％（P＜0．01）；垂体GH－mRNA水平提高了153．03％（P＜0．01）；下丘脑cAMP水平降低了21．89％（P＜0．01）；腺垂体中cAMP水平升高88．57％（P＜0．05）。
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| 关 键 词： | 肥育猪 N－甲基－D L－天冬氨酸 生长激素基因 表达 |
| 文章编号： | 1005-4545(2001)06-0631-03 |
| 修稿时间： | 2000-10-28 |
Effects of N-methyl-D,L-aspartate (NMA) on GH Gene Expression in Finishing Swine |
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| XU Zi-rong,LU Jian-jun,XIAO Ping. Effects of N-methyl-D,L-aspartate (NMA) on GH Gene Expression in Finishing Swine[J]. Chinese Journal of Veterinary Science, 2001, 21(6): 631-633 |
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| Authors: | XU Zi-rong LU Jian-jun XIAO Ping |
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| Abstract: | Eighty-four finishing pigs of the live weight from 56 to 90 kg were used to study the effect of NMA on GH gene expression.The results of feeding trial showed that 50 mg/kg NMA supplementation improved the average daily gain (ADG) by 9.31%(P<0.01) and decreased the feed gain ratio(F/G) by 7.16%.Adding NMA had no significant effects on the feed intake(P>0.05).Assay of sample indicated that addition of 50 mg/kg NMA decreased the cAMP concentration in hypothalamus by 21.89%(P<0.01),whereas increased the cAMP concentration in pituitary gland by 88.57%.It was found that the addition of 50 mg/kg NMA enhanced the level of pituitary GH-mRNA by 153.03%(P<0.01).The results implicated that the addition of 50 mg/kg NMA in diet would improve the level of GH-mRNA in pituitary gland and promote the growth of pigs by enhancing the level of GH. |
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| Keywords: | finishing pigs N-methyl-D L-aspartate GH gene expression |
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