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The antifeedant effect of some new withanolides on three insect species,spodoptera littoralis,epilachna varivestis andtribolium castaneum |
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| Authors: | K R S Ascher Miriam Eliyahu E Glotter A Goldman I Kirson A Abraham M Jacobson H Schmutterer |
| Institution: | 1. Dept. of Toxicology, ARO, The Volcani Center, Bet Dagan, Israel 2. Dept. of Biochemistry and Human Nutrition, Faculty of Agriculture, The Hebrew University of Jerusalem, Rehovot, Israel 3. Biologically Active Natural Products Laboratory, Agricultural Environmental Quality Institute, Beltsville Agricultural Research Center, MD 20705, Beltsville, U.S.A 4. Institute of Phytopathology and Applied Zoology, Justus-Liebig University, Giessen, West Germany |
| Abstract: | The antifeedant effect of several new withanolides on larvae ofSpodoptera littoralis, Epilachna varivestis andTribolium castaneum was investigated. 2,3-Dihydrowithanolide E (II) was an antifeedant forS. littoralis andE. varivestis; nicalbin A (XIV), and a mixture of withanicandrin (IX) and daturalactone A (X), were active against E. varivestis andT. castaneum. Some activity was shown by 6β,14α,17β,20αF-tetrahydroxy-1-oxowitha-2,4,24-trienolide (V) againstS. littoralis; 4β,5β-epoxy-6α,14α,17β,20αF-tetrahydroxy-l-oxowitha-2,24-dienolide (VII) againstE. varivestis andT. castaneum; 5α,6α,-epoxy-14α,17β,20αF-trihydroxy-1-oxowitha-2,24-dienolide (VI) againstE. varivestis; and nicalbin B (XV) againstT. castaneum. |
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