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雏鸡感染传染性法氏囊病毒后血液的T细胞变化
引用本文:魏萍,刘忠贵.雏鸡感染传染性法氏囊病毒后血液的T细胞变化[J].东北农业大学学报,1989(4).
作者姓名:魏萍  刘忠贵
作者单位:东北农学院病理教研室,东北农学院病理教研室
摘    要:本项研究对雏鸡感染传染性法氏囊病毒(IBDV)后,1~8周外周血液的 ANAE~+淋巴细胞(T 细胞)、淋巴细胞和白细胞数量的动态变化进行了检测。结果表明,1日龄雏鸡感染 IBDV 后,其血液中 ANAE~+,淋巴细胞数量明显低于对照雏鸡,表明其细胞免疫机能降低;4周龄雏鸡感染 IBDV 后,其 ANAE~+淋巴细胞数量呈一过性降低,变化不如1日龄感染雏鸡明显,说明 IBDV 对雏鸡存在感染年龄差异;对 ANAE~+淋巴细胞绝对数的检测较百分比能更真实地反映 IBD 鸡的细胞免疫功能变化的实质。

关 键 词:雏鸡  传染性法氏囊病毒  外周血液  T  细胞绝对数

IMMUNOLOGICAL DYNAMIC CHANGES OF TLY MPHOCYTES IN YOUNG CHICKENS INFECTED WITH INFECTIOUS BURSAL DISEASE VIRUS(IBDV)
Wei Ping Liu Zhonggui.IMMUNOLOGICAL DYNAMIC CHANGES OF TLY MPHOCYTES IN YOUNG CHICKENS INFECTED WITH INFECTIOUS BURSAL DISEASE VIRUS(IBDV)[J].Journal of Northeast Agricultural University,1989(4).
Authors:Wei Ping Liu Zhonggui
Abstract:Immunological dynamic variations of the number of leukocytes,lymphocytesand ANAE~+ lymphocytes were studied in the peripheral blood of chickensinfectd with IBDV.The results were as follows:1.The ANAE~+ lymphocytenumber decreased markedly in peripheral blood after IBDV infection at one-dayage,it showed that the function of cellular immunity declined;2.The totalnumber of lymphocytes and leukocytes decreased markedly after IBDV infection.It showed that IBDV infection could lead to the inhibition of immune functionin chickens;3.The changes of cellular immune functions in absolute numbermeasuring of ANAE~+ lymphocytes were more distinct than percentage measuringin fact;4.Inhibition of immune function of one day-old iafected chickenwas more significant than that of four-week-old ones.It showed a certaindifference in infection ages.
Keywords:chick  infectious bursal disease virus  peripheral blood  absolute number of ANAE~+ lymphocytes
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