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RNA沉默—新型的植物病毒病害防治策略
引用本文:牛颜冰,郭失迷,宋艳波,雷万钧,申林炎. RNA沉默—新型的植物病毒病害防治策略[J]. 中国生态农业学报, 2005, 13(2): 47-50
作者姓名:牛颜冰  郭失迷  宋艳波  雷万钧  申林炎
作者单位:山西农业大学,太谷,030801
基金项目:山西农业大学优秀人才引进基金项目,山西农业大学博士启动基金项目
摘    要:植物RNA沉默(RNAsilencing)是植物本身固有的一种抗病毒防御系统,是对病毒在复制过程中形成双链RNA(dsRNA)的特殊反应。RNA沉默介导的dsRNA干涉病毒侵染转基因抗病毒有其不足,几种体外生产dsRNA的抗病毒体系能弥补这一不足,它们与转基因表达病原RNA不同,但仍然依赖RNA沉默机制来获取病原抗性。综述了近年来发展起来的各种启动RNA沉默的dsRNA产生策略、抗病状况和存在的问题及发展前景

关 键 词:RNA沉默  双链RNA  抗病毒
收稿时间:2004-08-16
修稿时间:2004-08-16

RNA silencing-a new strategy for the control of virus diseases in plants
NIU Yan-Bing,GUO Shi-Mi,SONG Yan-Bo,LEI Wan-Jun and SHEN Lin-Yan. RNA silencing-a new strategy for the control of virus diseases in plants[J]. Chinese Journal of Eco-Agriculture, 2005, 13(2): 47-50
Authors:NIU Yan-Bing  GUO Shi-Mi  SONG Yan-Bo  LEI Wan-Jun  SHEN Lin-Yan
Affiliation:Shanxi Agricultural University,Taigu 030801,China;Shanxi Agricultural University,Taigu 030801,China;Shanxi Agricultural University,Taigu 030801,China;Shanxi Agricultural University,Taigu 030801,China;Shanxi Agricultural University,Taigu 030801,China
Abstract:RNA silencing occurs in plants is conceived as a natural antiviral defense system that is activated as a response to double?stranded RNA (dsRNA) formed during virus replication.To compensate for the disadvantages on RNA silencing by using dsRNA to specifically interfere with virus infection in transgenic plants,several approaches of obtaining dsRNA used for virus?resistance have been developed which differ from strategies based on transgenic expression of RNAs but still rely on RNA silencing as a means to achieve pathogen?derived resistance (PDR).In this paper,the dsRNA produce strategies for RNA silencing,their applications for virus resistance,disadvantages and perspectives are reviewed.
Keywords:RNA silencing  Double?stranded RNA  Virus resistance
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