Temporal frequency of subthreshold oscillations scales with entorhinal grid cell field spacing |
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| Authors: | Giocomo Lisa M Zilli Eric A Fransén Erik Hasselmo Michael E |
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| Affiliation: | Center for Memory and Brain, Department of Psychology, Program in Neuroscience, Boston University, 2 Cummington Street, Boston, MA 02215, USA. giocomo@bu.edu |
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| Abstract: | Grid cells in layer II of rat entorhinal cortex fire to spatial locations in a repeating hexagonal grid, with smaller spacing between grid fields for neurons in more dorsal anatomical locations. Data from in vitro whole-cell patch recordings showed differences in frequency of subthreshold membrane potential oscillations in entorhinal neurons that correspond to different positions along the dorsal-to-ventral axis, supporting a model of physiological mechanisms for grid cell responses. |
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