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| 微生物发酵产生他汀类化合物的研究进展 | |
| 引用本文： | 程文娟,杨大鹏,顾丰颖,李昆仑.微生物发酵产生他汀类化合物的研究进展[J].农产品加工．学刊,2011(2):76-80. |
| 作者姓名： | 程文娟 杨大鹏 顾丰颖 李昆仑 |
| 作者单位： | 1. 天津农业资源与环境研究所,天津,300192 2. 三门峡市质量技术监督检验分析测试中心,河南,三门峡,472000 3. 浙江大学,生命系统工程与食品科学学院,浙江,杭州,310058 4. 国家农产品保鲜工程技术研究中心,天津,300384 |
| 摘 要： | 他汀类化合物作为有效的降脂类药物得到广泛的研究。目前他汀类产品主要来自于微生物发酵的次级代谢产物以及化学合成。从菌种选育、发酵条件、他汀类化合物的微生物转化、组合生物合成技术的应用等方面,对微生物生产他汀进行综述。 |
| 关 键 词： | 微生物发酵 他汀 菌种选育 微生物转化 组合生物合成 |
Advances in Production of Statins by Microbe Fermentation |
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| Cheng Wenjuan,Yang Dapeng,Gu Fengying,Li Kunlun.Advances in Production of Statins by Microbe Fermentation[J].Nongchanpin Jlagong.Xuekan,2011(2):76-80. | |
| Authors: | Cheng Wenjuan Yang Dapeng Gu Fengying Li Kunlun |
| Institution: | 1.Institute of Tianjin Agricultural Resources and Environment,Tianjin 300192,China;2.Center of Sanmenxia Quality Technology Supervision and Inspeetion Analsis and Test,Sanmenxia,He’nan 472000,China;3.School of Biosystems Engineering and Food Science,Zhejiang University,Hangzhou,Zhejiang 310058,China;4.Research Center of National Agricultural Fresh-keeping Engineering Technology,Tianjin 300384,China) |
| Abstract: | As a kind of effective cholesterol-lowering agents the statins have been studied widely.Generally,the products about statins mainly comes from secondary metabolite of microbe or chemical synthesis.This paper reviews production of statins by microbe fermentation from strain improvement,fermentation condition,microbial conversion,combinatorial biosynthesis. |
| Keywords: | microbe fermentation Statins strain improvement microbial conversion combinatorial biosynthesis |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |