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Mice inoculated with marek's disease tumor cells: Increased number of lymphomas
Authors:Mary Ann Amos  Anne H Nielsen  Alvar A Werder
Affiliation:1. Department of Microbiology, University of Health Sciences College of Osteopathic Medicine, 2105 Independence Avenue, Kansas City, MO 64124 U.S.A.;3. Department of Microbiology, University of Kansas Medical Center, College of Health Sciences and Hospital, Kansas City, KS 66103 U.S.A.
Abstract:Germfree derived CFWwd mice were inoculated with tumor cells from chickens with Marek's disease and observed for any long term effect. Nineteen per cent of these animals developed tumors whereas the incidence in control animals was 0.2%. Of those animals which developed tumors, 62% of the animals were observed to have ataxia before tumor development. Marek's disease herpesvirus was never observed in any of the murine tumors.
Keywords:Marek's disease  murine lymphomas  Maladie de Marek  lymphome de la souris
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