| 亚硒酸钠缓释剂的制备 |
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| 引用本文： | 梁贞兰,李松月,许应天. 亚硒酸钠缓释剂的制备[J]. 延边大学农学学报, 2009, 31(1): 62-66 |
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| 作者姓名： | 梁贞兰 李松月 许应天 |
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| 作者单位： | 1. 延吉市动物卫生检疫站,吉林,延吉,133000
2. 延边大学农学院,吉林,龙井,133400 |
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| 摘 要： | 以β-环状糊精为载体，以缓释效果为指标，选用饱和溶液法制备亚硒酸钠缓释剂．采用正交试验对缓释剂的制备条件进行优化，筛选出最佳制备条件，并用透析法检测其体外释放效果．试验结果表明，亚硒酸钠缓释剂释放速度明显慢于亚硒酸钠水溶液，制备亚硒酸钠β-CD缓释剂的最佳工艺条件为：温度20℃，搅拌时间3h，亚硒酸钠与β-CD投料体积比为1：3．
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| 关 键 词： | 亚硒酸钠 β-环状糊精 缓释剂 缓释效果 |
Prepare the Sodium Selenite slow release medicinal preparation |
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| LIANG Zhen-lan,LI Song-yue,XU Ying-tian. Prepare the Sodium Selenite slow release medicinal preparation[J]. Journal of Agricultural Science Yanbian University, 2009, 31(1): 62-66 |
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| Authors: | LIANG Zhen-lan LI Song-yue XU Ying-tian |
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| Affiliation: | LIANG Zhen-lan , LI Song-yue, XU Ying-tian(1. Animal Health and Epidemic-prevention Station of Yanji ,Yanji Jilin 133000,China; 2. Agricultural College of Yanbian University ,Longjing Jilin 133400, China) |
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| Abstract: | Make the β-cyclodextrin as carrier to prepare Sodium Selenite slow release medicinal preparation. Then selected the best preparation conditions by orthogonal test, and compared release effect with Sodium Selenite slow release medicinal preparation and aqueous solution of sodium selenite. Release results showed that the sodium selenite retarder was obviously slower than aqueous solution of sodium selenite, and basic achieve the desired release results. Through the orthogonal experiment, the optimum conditions to prepare β-CD Sodium Selenite slow release medicinal preparation is the volume ratio between Sodium Selenite and β-CD was 1 ： 3 at 20 ℃ for 3 hours. |
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| Keywords: | Sodium Selenite β-cyclodextrin slow release medicinal preparation slow release effect |
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