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Intra-articular Infection by Scedosporium prolificans in a Horse
Authors:Sara D Lawhon  Deanna A Sutton  Natalie D Halbert  Jeffrey P Watkins
Institution:a Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX
b Department of Pathology, Fungus Testing Laboratory, University of Texas Health Science Center, San Antonio, TX
c Department of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX
Abstract:Two months following the surgical repair of an acute, open, comminuted, and articular fracture of the left olecranon, a 15-year-old American Saddlebred gelding presented with nonweight-bearing lameness. A fungus cultured from the cubital joint was identified as Scedosporium prolificans by sequencing of the D2 large subunit ribosomal DNA region and subsequently confirmed by phenotypic methods. Therapy with systemic fluconazole, terbinafine and intra-articular voriconazole was attempted, but was unsuccessful.
Keywords:Equine  Scedosporium  Osteomyelitis  Sequencing  D1-D2 ribsomal subunit
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