| 口蹄疫病毒全基因组序列特征分析 |
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| 引用本文： | 杨鹏华,倪凤娥.口蹄疫病毒全基因组序列特征分析[J].河南农业科学,2011,40(11):140-144. |
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| 作者姓名： | 杨鹏华 倪凤娥 |
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| 作者单位： | 长江大学生命科学学院长江中游湿地农业教育部工程研究中心,湖北荆州,434025 |
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| 基金项目： | 转基因生物新品种培育科技重大专项 |
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| 摘 要： | 对口蹄疫病毒全基因组序列特征的分析有助于了解口蹄疫病毒复制、翻译等生命活动的相关机制.利用DNAStar和DNAMAN软件,对249株口蹄疫病毒全基因组序列进行了比对分析.结果表明,口蹄疫病毒ORF的长度为5 982～7 020 bp,平均长度为6 975 bp,编码1 994～2 340个氨基酸.各基因的核酸序列同源...
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| 关 键 词： | 口蹄疫病毒 序列比对 基因组 |
Sequence Analysis of the Foot and Mouth Disease Virus Genome |
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| YANG Peng-hua,NI Feng-e.Sequence Analysis of the Foot and Mouth Disease Virus Genome[J].Journal of Henan Agricultural Sciences,2011,40(11):140-144. |
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| Authors: | YANG Peng-hua NI Feng-e |
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| Institution: | (Engineering Research Center of Wetland Agriculture in the Middle Reaches of the Yangtze River, Ministry of Education,College of Life Science,Yangtze University,Jingzhou 434025,China) |
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| Abstract: | There was no much information about the life circle of foot and mouth disease virus(FMDV),such as replication,translation as well as assembly of virus.Analysis of the FMDV genome may provide a chance to discover the mystery to some extent.Presently,the genomes of 249 FMDV isolates were aligned by the biological software,DNAStar and DNAMAN.The lengths of the open reading frame(ORF) in all isolates were between 5 982 to 7 020 bp,which code 1994 to2 340 amino acids.The homology of all genes of FMDV was above 74% and up to 94.29%.Three long conserved sequences and four conserved motifs were obtained in the 5′-UTRs and 3′-UTRs of FMDV,respectively.The result provided a new basis for understanding the relationshipbetween the genome sequence and life mechanism of FMDV. |
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| Keywords: | Foot and mouth disease virus Sequence alignment Genome |
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