Nephrotic syndrome associated with administration of sulfadimethoxine/ormetoprim in a dobermann |
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Authors: | Vasilopulos R J Mackin A Lavergne S N Trepanier L A |
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Institution: | Department of Clinical Sciences, Mississippi State University College of Veterinary Medicine, Starkville, Mississippi, USA. |
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Abstract: | This case report describes sulphonamide-induced nephrotic syndrome in a young dobermann dog. The clinical signs and laboratory abnormalities resolved shortly after discontinuation of the sulphonamide antibiotic and with generalised supportive care. Since nephrotic syndrome typically carries a guarded prognosis in veterinary medicine and is poorly responsive to therapy, a thorough drug history should be an important part of the investigation of any animal with a protein-losing nephropathy. |
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