| 不同取代度羧甲基壳聚糖的抗氧化性能研究 |
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| 引用本文： | 姚倩,孙涛,周冬香,毛芳.不同取代度羧甲基壳聚糖的抗氧化性能研究[J].安徽农业科学,2008,36(16):6620-6621. |
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| 作者姓名： | 姚倩 孙涛 周冬香 毛芳 |
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| 作者单位： | 上海水产大学食品学院,上海,200090;上海水产大学食品学院,上海,200090;上海水产大学食品学院,上海,200090;上海水产大学食品学院,上海,200090 |
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| 基金项目： | 上海市教育委员会科研项目
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上海市重点学科建设项目专项基金 |
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| 摘 要： | 目的]为了研究羧甲基壳聚糖的取代位置、取代度及其抗氧化功能之间的关系。方法]低聚壳聚糖经醚化得到3种取代度不同的N,O-羧甲基壳聚糖-NOA,NOB和NOC,并对其结构和取代度进行了表征,考察了它们对羟自由基的清除作用。结果]NOA,NOB和NOC清除羟自由基的半抑制浓度分别为0.15,0.29和0.23 mg/ml。而NOA,NOB和NOC在氨基上的取代度分别为0.51,0.29和0.38,羟基取代度分别为0.74,0.84和0.97结论]随着氨基位置取代度的升高,N,O-羧甲基壳聚糖清除羟基自由基的能力逐渐增强。
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| 关 键 词： | 低聚壳聚糖 羧甲基壳聚糖 取代度 羟基自由基 |
| 文章编号： | 0517-6611(2008)16-06620-02 |
| 修稿时间： | 2008年3月25日 |
Antioxidant Activity of Carboxymethyl Chitosan with Different Substituted Degrees |
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| YAO Qian.Antioxidant Activity of Carboxymethyl Chitosan with Different Substituted Degrees[J].Journal of Anhui Agricultural Sciences,2008,36(16):6620-6621. |
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| Authors: | YAO Qian |
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| Abstract: | Objective]In order to study the relations among different positions,degrees of substitution and antioxidant ability.Method] N,O-carboxymethyl chitosan(NOA,NOB and NOC)with various degrees of substitution(DS)were obtained by etherizingchito-oligosacchaside.Their structure and substituted degree were characterized and their antioxidant activity to ·OH was evaluated.Result]The IC50 s of NOA,NOB and NOC were 0.15,0.29,0.23 mg/ml while their DSs of NH2 position(DSN) were 0.51 0.29 and 0.38 and DSO were 0.74,0.84,0.97respectively.Conclusion]With the increase of DSN,antioxidant activity of N,O-carboxymethyl chitosan oligosaccharide to ·OH was up. |
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| Keywords: | Chitosan oligosaccharide Carboxymethyl chitosan oligosaccharide Substituting degree Antioxidant activity |
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