| 大鼠胆酸负荷对肝脏某些功能影响的研究 |
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| 引用本文： | 时浩,张克春,毛鑫智. 大鼠胆酸负荷对肝脏某些功能影响的研究[J]. 上海交通大学学报(农业科学版), 1999, 0(1) |
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| 作者姓名： | 时浩 张克春 毛鑫智 |
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| 作者单位： | 上海医科大学实验动物部，上海市农场管理局畜牧兽医站，南京农业大学动物医学院 |
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| 摘 要： | ＳＤ大鼠尾静脉给予胆酸，观察胆酸在体内的代谢过程及其对肝脏抗氧化酶话力和肝脏特异的白蛋白（Ａ）的影响，结果表明：血清甘胆酸（ＣＧ）水平以中胆酸组升高最为显著；大鼠肝组织匀浆中超氧化物歧化酶（ＳＯＤ）、谷胱甘肽过氧化物酶（ＧＳＨ－ＰＸ）和过氧化氢酶（ＣＴ）三种酶的活力从对照组到低、中胆酸组依次升高，高胆酸组均降低。血清白蛋白（川的水平以高胆酸组变动为最为显著。
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| 关 键 词： | SD大鼠，胆酸，抗氧化酶活力，白蛋白 |
EFFECTS OF EXOGENOUS CHOLIC ACID ONTHE LIVER IN SD RATS |
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| Shi Hao,Zhang Kechun,Mao Xinzhi. EFFECTS OF EXOGENOUS CHOLIC ACID ONTHE LIVER IN SD RATS[J]. Journal of Shanghai Jiaotong University (Agricultural Science), 1999, 0(1) |
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| Authors: | Shi Hao Zhang Kechun Mao Xinzhi |
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| Affiliation: | Shi Hao, Zhang Kechun, Mao Xinzhi3 |
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| Abstract: | Thirty - two female SD rats were given different doses of exogenous cholic acid. The effect on the liverfunctions was shown as follows: CG levels in the serum increased to a significant extent in the medium concentrationgroup compared with the control. The activity of SOD, GSH - PX and CT in the liver homogenate varied regularly,increasing progressively from control, low to medium concentration group, then decreasing in high concentrationgroup. Serum album dropped significantly in the high concentration group. |
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| Keywords: | SD rats Exogenous cholic acid Enzyme activity Serum album |
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